Anti-Cancer Potential Involved With The Antioxidant Mechanisms Of Herbs


  • B. Bhargavi and P. Shanmugasundaram*


Anticancer, Antioxidant, Herbal leads, ROS, Oxidative stress


Cancer is a concoction of diseases that are inter-related. It is a consequence and cause of many related disorders. Although there exist many types of cancers and every cancer starts with an abnormality in the multiplication and growth of cells. Cancers are the current global challenge and are the most significant cause of mortality in the world due to medical reasons. It is also a leading reason for the mortality in developed countries, and almost 0.8 million deaths were recorded in every 5 million cancer cases yearly in India. There are various treatment protocols like chemotherapy, Surgery, Radiation therapy and immunotherapy. However, the complete recovery of the patients from cancer is still questionable with these treatment options. The available synthetic anticancer drugs are reported to exhibit toxicity towards normal tissues and have undesirable side effects. The non-discriminatory use of these drugs leads to severe consequences in normal cells with the high proliferative index, leading to drug resistance and limiting the effective dose of anticancer drug that can be administered. The herbs and the herbal lead molecules that are extracted and isolated has a significant anticancer activity and antioxidant activity that are correlated with each other and are considered safe and effective compared to synthetic drugs. Majorly the antioxidant activity of those herbs is the basis of the treatment of cancer which enables newer pathways in the cancer treatment which enables to extend our horizon to treat deadly cancer in a safer and effective manner.