http://actafarmbonaerense.com.ar/index.php/latamjpharm <div align="justify"><strong><em>Latin American Journal of Pharmacy</em> (formerly <em>Acta Farmacutica Bonaerense</em>) ISSN 0326 2383</strong> is the scientific journal of the College of Pharmacists of Buenos Aires Province, Argentina. The journal publishes research reports in the form of original articles or short communications on most aspects of pharmaceutical sciences, with strong emphasis on originality and scientific quality. More specifically, but not exclusively, the journal publishes mainly reports in medicinal chemistry, pharmacology, drug absorption and metabolism, pharmacokinetics and pharmacodynamics, pharmaceutical and biomedical analysis, drug delivery, pharmaceutical technology and biotechnology, pharmaceutical care, and clinical drug evaluation. Reviews or mini-reviews are not encouraged, but experimental articles are privileged. Articles reporting the isolation of secondary metabolites of plants will be only considered if biological and toxicological assays are included. In general, reports on biological activities of crude extracts are not considered for publication unless any bioactive compound is isolated and identified. Contributions reporting unexceptional and predictable bioactivity (for instance, antioxidant activity of extracts or antimicrobial activity of essential oils) are not normally considered for publication.<br /><br />Articles are indexed and abstracted in Chemical Abstracts Service, International Pharmaceutical Abstracts Service, BioScience Information Service (Biological Abstracts), Periodica (Index of Latin American Scientific Journals), International Pharmaceutical Technology &amp; Product Manufacture Abstracts, Referativnyi Zhurnal (Institut of Scientific Information, Russian Academy of Sciences), EMBASE/Excerpta Medica, LILACS (Latin American and Caribbean Health Sciences Literature) and LATINDEX. The journal was awarded in 1986 and 2000 with APTA-Antonio Rizzuto prize (scientific journals category) and in 2002 was qualified as scientifical journal level one (excellent) by the Argentine Center of Scientific and Technological and Information (CAICYT-.CONICET) within the LATINDEX Project, integrantes the Common Core of Argentinian Scientific Journals and has been proclaimed as a journal of provincial interest by the Honorable Deputy Chamber of Buenos Aires Province, Argentina.<br />From 2017, <em>Lat. Am. J. Pharm.</em> publishes twelve issues per year</div> Colegio de Farmaceuticos de la Provincia de Buenos Aires en-US Latin American Journal of Pharmacy : A Life Science Journal http://actafarmbonaerense.com.ar/index.php/latamjpharm/article/view/923 <p>Impurity profiling is a crucial aspect of pharmaceutical analysis, aimed at ensuring the safety, efficacy, and quality of drug products. The presence of impurities, even at trace levels, can significantly impact the pharmacological properties of pharmaceuticals, posing risks to patient health. This review provides an in-depth examination of impurity profiling methodologies, recent advancements, challenges, and future perspectives in the field. Various analytical techniques, including chromatography, spectroscopy, and mass spectrometry, are discussed, along with regulatory requirements and industry practices. Furthermore, emerging trends such as the application of artificial intelligence and automation in impurity profiling are explored, highlighting their potential to revolutionize pharmaceutical analysis.</p> Ms. Priyanka R. Varade*, Dr. Moreshwar P. Mahajan Copyright (c) 2024 2024-04-19 2024-04-19 43 4 1 7 http://actafarmbonaerense.com.ar/index.php/latamjpharm/article/view/924 <p>The objective of review is to explore various aspects hot melt coating (HMC) technology in the drug product manufacture. Global market drivers for oral solid dosage (OSDs) forms are generic market, newer indications of existing drugs, new combinations, life cycle extension of available drugs etc. To meet the needs of market and regulatory bodies, the melt coating technology can resolve the drug related issues of bioavailability, economy, formulation, stability and scalability. The HMC is rapid, reliable, cost-effective and environment friendly technique. Neither aqueous nor organic solvents are required for drug product design in this technique. The regulatory bodies are currently focusing on environment sustainability and safety issues which are strictly followed by this technology. The simple pan coaters or fluidized bed coaters with minor modification were deployed in this technology. It offers several applications in dosage form design. It is user friendly as most of lipid materials are used for coating which facilitate easy gliding of dosage form into gastrointestinal tract (GIT).</p> Lakade S. K., Rakte A. S., Sudke S. G.* Copyright (c) 2024 2024-04-19 2024-04-19 43 4 8 16