A Prospective Randomized Comparative Study Between Efficacy Of Chlorhexidine Gluconate Alcohol Scrub And 7.5% Povidone Iodine Scrub And Effect Of 1 Minute Versus 5 Minutes Versus 10 Minutes Contact Time In Preoperative Skin Preparation In Elective Groin H

Abstract

Surgical Site Infections (SSIs) have been the most common complication of both clean and contaminated surgeries. The World Health Organization has suggested 26 recommendations with a global perspective with respect to benefits versus harms, evidence quality level, cost efficacy and resource use implications and patient values and preferences. In that 26 recommendations, WHO has recommended alcohol-based Chlorhexidine and has implied that their use can be an additional cost factor for health care facility and has suggested local manufacture at large scale to support resource availability and this recommendation has been termed low to moderate. We are in a developing, highly populous country, planned to compare the efficacy of alcohol-based Chlorhexidine gluconate scrub with most easily accessible and available 7.5% povidone Iodine scrub solution with ideal contact time analysis in prevention of surgical site infections in a clean common Hernioplasty surgery in a tertiary care institution. Our study found the superiority of Chlorhexidine in reducing skin flora, but there was no difference in efficacy in reducing both Superficial and Deep-seated surgical site infections and minimal contact time we advocated had the same efficacy compared to higher contact time in reducing Surgical site infections.