Formulation And Evaluation of Herbal Emulgel for The Wound Healing Activity

Abstract

The aim of the study is to develop and assess the wound healing activity of an herbal emulgel using Celosia argentea leaves extract and sesame oil. The reason behind the selection of drugs is to minimize the side effects, cost, and reduce toxicity of synthetic drugs. The emulgel was prepared using Carbopol 940 as a gelling agent, methyl and propyl parabens as preservatives, propylene glycol as a humectant, and Span 20 and Tween 20 as surfactants. The emulgel was evaluated for various parameters such as pH, viscosity, spreadability, drug content, and in-vitro drug release, and the optimized batch was found to be F7, with a pH of 6.36, viscosity of 19273CP, spreadability of 19.237(gm.cm/sec), drug content of 94.44%, and in-vitro drug release of 89.6875%. This study highlights the potential of herbal emulgel in promoting wound healing activity and supports the use of Celosia argentea extract and sesame oil in the development of such formulations.