A Short Review Of Current Trends, Impending Obstacles, Modern Synthetic Approach, Structure Activity Relationship And Numerous Biological Activities Of Benzimidazole

Abstract

O-phenylenediamine and formic acid are condensed to create the commercially accessible benzimidazole. The most common benzimidazole substance found in nature is N-riosyldimethylbenzimidazole, which functions as an axial ligand for cobalt in vitamin B12. The therapeutic properties of benzimidazole and its derivatives, such as those found in anthelmintic and antiulcer medications, are crucial. In addition, the benzimidazole derivatives show pharmacological effects such antibacterial, antiviral, anticancer, anti-inflammatory, and analgesic properties. This article summarizes the substituted benzimidazoles so that readers may learn about their chemistry and pharmacological properties.