Design And Optimization Of Antipsychotic Polymeric Nanocapsules

Authors

  • Sreekanth M C , Muruganantham V, B.S Venkateswarlu, R Margaret Chandira, S. Shanmuganathan

Keywords:

Nanocapsules, Paliperidone palmitate, polycaprolacone, Poloxamer, Zetapotential

Abstract

The design and optimization of antipsychotic polymeric nanocapsules have emerged as a promising avenue for enhancing the therapeutic efficacy and reducing side effects of antipsychotic medications. Polymeric nanocapsules represent a versatile and effective platform for drug delivery due to their ability to encapsulate therapeutic agents within a biocompatible polymeric shell. Optimizing the antipsychotic polymeric nanocapsules requires a careful balance between drug release kinetics and stability during storage and circulation. The aim to achieve sustained drug release, maintaining therapeutic drug concentrations over an extended period while avoiding burst releases that might lead to toxic effects. The development of nanocapsules requires rigorous characterization techniques, including particle size analysis, drug encapsulation efficiency, drug release profiles, and stability assessments. In conclusion, the design and optimization of antipsychotic polymeric nanocapsules hold great promise for revolutionizing the treatment of psychiatric disorders.

Published

2023-08-10

Issue

Section

Articles