Pharmacokinetics and Pharmacodynamics: Current Concepts and Applications

Authors

  • Srinu Bhoomandla, Sreedhar Pandiri, Akarapu Premalatha, Konda Santosh Kumar

Keywords:

Pharmacokinetics, Pharmacodynamics, Drug absorption, Drug distribution, Drug metabolism, Drug excretion, Therapeutic effects, Drug interactions, Pharmacogenomics, Personalized medicine, Drug delivery systems, Computational modelling, Drug therapy, Individual variability

Abstract

This review aims to provide a comprehensive overview of current concepts and applications in the fields of pharmacokinetics and pharmacodynamics. Pharmacokinetics refers to the study of how a drug is absorbed, distributed, metabolized, and excreted by the body, while pharmacodynamics involves understanding the drug's effects on the body and the mechanisms underlying its actions. The interplay between pharmacokinetics and pharmacodynamics is crucial in optimizing drug therapy, ensuring safety, and achieving desired therapeutic outcomes. This review discusses recent advancements in technology and methodologies that have revolutionized the study of drug kinetics and dynamics, such as computational modelling, personalized medicine approaches, and innovative drug delivery systems. Additionally, the review highlights the importance of considering individual variability in drug response and the role of pharmacogenomics in tailoring treatments. By examining current research trends and real-world applications, this review sheds light on the evolving landscape of pharmacokinetics and pharmacodynamics, offering insights into how these disciplines contribute to enhancing patient care and drug development.

Published

2023-08-20

Issue

Section

Articles