Phytochemical and anticancerous potential of the fruit extract of annona muricata l.

Abstract

The objective of this research was to explore the preliminary phytochemical and anticancerous properties of Annona muricata fruit extract. The fruit parts like mesocarp and epicarp were selected for the study. Chloroform solvent is used for the extraction. The qualitative and quantitative analysis of the phytochemicals was determined. The anticancerous studies were made by MTT assay method. Various concentration of the extract was used for anticancerous analysis. The MCF-7 breast cancer cell line was used for the viability test and the IC 50 value was determined. The results of the qualitative and quantitative phytochemical analysis revealed the presence of alkaloids, flavonoids, tannins, phenols, terpenoids, glycosides, saponins, steroids, carbohydrates, reducing sugars and proteins. The phytochemical compounds were more in epicarp than mesocarp.The MCF-7 breast cancer cell line also showed the best results in mesocarp than epicarp.