Anti-Pyretic Effects Of Aqueous Extract Of Anogeissus Latifolia Roxb In Albino Wistar Rats

Abstract

The antipyretic effects of Anogeissus latifolia aqueous leaf extract on Wistar rats were studied. In total, 30 Wistar rats (both sexes) ranging in weight from 150 to 200 grams were employed. The fever was artificially induced with baker's yeast. There were five groups of rats. six rats in each study group. The third, fourth, groups got 200 and 400mg/kg b.w. of After induction, the aqueous extract and the control medication The first two groups were used as comparable negative and normal controls Blood samples were taken from slaughtered rats for blood tests, urine tests, and other biochemical tests. The plant's phytochemical profile revealed the Quinine, Tannins, Phenolic Compounds, and Alkaloids are all present. Significant results were found. Group 2 showed a statistically significant increased, rectal temperature, and Groups 2 and 3, while Group 5 showed a nonsignificant decrease in these metrics. respectively. C-reactive protein and nitric oxide levels both rose significantly (p 0.05). Studies found concentrations in groups 3 and 4 compared to group 2. All haematological indicators across all treatment groups showed no statistically significant differences. found, in contrast to the second group. Anogeissus latifolia, leaf aqueous extract showed after 4 hours of treatment, pyretic effects at 400mg/kg b.w.