Review on cancer in the perspective of Targeted therapies

Abstract

Cancer is a complex and heterogeneous disease characterized by uncontrolled cell growth and proliferation. Over the years, extensive research has been conducted to develop targeted anticancer drugs that specifically act on the underlying molecular alterations driving cancer progression. The advent of molecular profiling techniques and high-throughput sequencing technologies has enabled the identification of various genetic and epigenetic alterations associated with different types of cancer like breast cancer, oral cancer etc. The classification of targeted anticancer drugs can also be based on the specific molecular alterations they target, such as mutations in oncogenes or tumor suppressor genes, aberrant protein expression, or dysregulated signaling pathways. Precision medicine approaches have emerged, which utilize these molecular profiles to match patients with the most appropriate targeted therapies based on the specific genetic alterations present in their tumors. The classification of targeted anticancer drugs based on their targets and mechanisms of action provides valuable insights into their efficacy and potential applications in cancer treatment. Further advancements in molecular profiling techniques and personalized medicine approaches hold promise for the development of more effective and tailored therapies to combat cancer.