Antimicrobial Potential Of Blumea Lacera Against Disease Causing Clinical Bacterial Pathogens

Abstract

Blumea lacera are one of the important plant growth herb belongs to family Asteraceae. It is small annual herbs that are considered as renewable sources of various bioactive compounds and possess various medicinal properties that produce great variety of secondary metabolites with broad spectrum of biological activities. It is a well known for its folk dietary supplement consumed by the people living in coastal areas as it contains alkaloids, flavonoids, essential fatty acids, proteins, dietary fibers, carbohydrates as it has a great nutritive value. It has a wide application in pharmacological research such as analgesic, anti-inflammatory, anti-diarrheal, diuretic, and anthelmintic and has various antimicrobial and anti-oxidative properties. It shows many therapeutic activities such as hepatoprotective, antiulcer and has many other nutritional effects. B.lacera showed antimicrobial activity against plant pathogens and few bacterial pathogens but not much of hospital acquired bacterial clinical pathogens. In this study, we focused on the antimicrobial activity of Blumea lacera against eight clinical pathogenic bacteria (E.coli, Klebsiella pneumonia, MRSA, Proteus mirabilis, Salmonella typhii, Shigella sonnei, Pseudomonas aeruginosa, Acinetobacter baumanii. Blumea lacera was extracted by two different solvents such as methanol and aqueous solution. The antimicrobial activity was done by agar well diffusion method. In this study, we have shown that Blumea lacera has antimicrobial potential against the tested clinical bacterial pathogens. Methanol was found to be the best solvent for extraction and retention of the antimicrobial activity of this plant herb.